Skin rash in novel H7N9 influenza infection: a concern
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Pathogenicity of the Novel A/H7N9 Influenza Virus in Mice
UNLABELLED A novel avian-origin influenza A/H7N9 virus infecting humans was first identified in March 2013 and, as of 30 May 2013, has caused 132 human infections leading to 33 deaths. Phylogenetic studies suggest that this virus is a reassortant, with the surface hemagglutinin (HA) and neuraminidase (NA) genes being derived from duck and wild-bird viruses, respectively, while the six "internal...
متن کاملHuman infection with a novel avian-origin influenza A (H7N9) virus.
BACKGROUND Infection of poultry with influenza A subtype H7 viruses occurs worldwide, but the introduction of this subtype to humans in Asia has not been observed previously. In March 2013, three urban residents of Shanghai or Anhui, China, presented with rapidly progressing lower respiratory tract infections and were found to be infected with a novel reassortant avian-origin influenza A (H7N9)...
متن کاملHuman Infection with Avian Influenza a (h7n9) Virus
BACKGROUND Characterisation of the severity profile of human infections with influenza viruses of animal origin is a part of pandemic risk assessment, and an important part of the assessment of disease epidemiology. Our objective was to assess the clinical severity of human infections with avian influenza A H7N9 virus, which emerged in China in early 2013. METHODS We obtained information abou...
متن کاملAdaptation of novel H7N9 influenza A virus to human receptors
The emergence of the novel H7N9 influenza A virus (IAV) has caused global concerns about the ability of this virus to spread between humans. Analysis of the receptor-binding properties of this virus using a recombinant protein approach in combination with fetuin-binding, glycan array and human tissue-binding assays demonstrates increased binding of H7 to both α2-6 and α2-8 sialosides as well as...
متن کاملPopulation-Level Antibody Estimates to Novel Influenza A/H7N9
There are no contemporary data available describing human immunity to novel influenza A/H7N9. Using 1723 prospectively collected serum samples in southern Vietnam, we tested for antibodies to 5 avian influenza virus antigens, using a protein microarray. General-population antibody titers against subtype H7 virus are higher than antibody titers against subtype H5 and lower than titers against H9...
متن کاملGlobal concerns regarding novel influenza A (H7N9) virus infections.
S disease in humans caused by a novel influenza A virus that is distinct from circulating human influenza A viruses is a seminal event. It might herald sporadic human infections from an animal source — e.g., highly pathogenic avian influenza (HPAI) A (H5N1) virus; or it might signal the start of an inf luenza pandemic — e.g., influenza A(H1N1)pdm09 virus. Therefore, the discovery of novel influ...
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عنوان ژورنال
دوره 16 شماره 3
صفحات 120- 120
تاریخ انتشار 2013-07-01
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